Professor George Fleming was the Stanford University professor who conspired with Bryce Larkin to expel Chuck from the University for cheating on a test. In truth, Fleming was planning on recruiting Chuck for the CIA's Omaha project, but Chuck's roommate, Bryce Larkin, intercepted the professor's call and told Fleming that Chuck was too good-hearted to survive as the same person in a military op like Omaha, and he wanted Chuck left out of it. Fleming told him the CIA would not accept a refusal from so promising a canditate, therefore, they came up with a plan to get Chuck's test results negated, even if it meant his expulsion.
In 2007, Fleming had to run from Magnus Einerson, an Icelandic assassin, who was looking for Fleming's files on all the CIA recruits at Stanford. He arrives in Los Angeles, where he was found by Chuck, now the Intersect. Relieved at finding an ally, Fleming tells Chuck a code phrase, "Are you coming to the toga party?" in case of emergency.
Chuck felt he had to ask Fleming about his expulsion, but before Fleming could tell Chuck why he was expelled, Einerson shoots him in the back with his crossbow. Before slipping into unconsciousness, Fleming gave Chuck a list of numbers and asks that he give to Bryce Larkin, unaware Larkin is presumed dead. The numbers lead to a drop he and Bryce used in the library at Stanford. When he next saw her, Sarah told Chuck that Fleming was in surgery.
Chuck later used Fleming's emergency phrase to rally CIA recruits at Stanford to stop Einerson.
- According to Chuck's Tron Poster, Fleming's CIA code name is Glass Castle and he received his M.A. and Ph.D. at Yale University.