Lou's Gourmet Italian Deli is a sandwich shop located in Burbank in the same shopping plaza as the Buy More, and is owned by Lou Palone. It is featured in "Chuck Versus the Truth" and forms a key plot location in "Chuck Versus the Imported Hard Salami".
Chuck visits the deli often during "Chuck Versus the Truth" and "Chuck Versus the Imported Hard Salami" during his short-lived romance with Lou. She even names a turkey and Muenster sandwich on egg bread "The Chuck Bartowski" after he fixed her phone for her.
Chuck has to apologize profusely, however, having upset her on their first date at Club Ares the previous night, when he was on mission at the same time, unbeknownst to her. Eventually he discovers she has been illegally importing meats which must normally first pass customs checks but Team Bartowski had originally mistaken this for her being involved in weapons smuggling with Stavros Demetrios; her ex boyfriend.
After "Chuck Versus the Imported Hard Salami", neither Lou nor the deli are seen again.